#YOLO is a popular meme on the internet, which means "You only live once" and is usually given as an explanation for doing something incredibly stupid and dangerous.
The slogan is shown on this design above a suitably amusing situation, in which a stick man deliberately crashes a car into a wall, allowing himself to be thrown through the windshield, over a fire and a spiky cactus, so that he can fall into the open arms of a waiting stick-maiden on a bed.